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In 1943, Albert Schatz, a young PhD student at New Jersey's Rutgers Agricultural College, was working on a wartime project testing bacteria from farmyard soil when he discovered streptomycin, a new antibiotic that was the first effective drug against the global killer tuberculosis. Schatz’s professor, Selman Waksman, claimed all credit for the discovery, calling Schatz a mere bench worker, and secretly enriched himself with royalties once the drug was patented by pharmaceutical manufacturer Merck. Schatz fought back in what was one of the most vicious battles ever for credit of a major scientific discovery. Schatz won the title of "co- discoverer" and a share of the royalties, but, in 1952, Waksman alone was awarded a Nobel Prize. Schatz disappeared into academic obscurity.
This Medical Center Hour features journalist Peter Pringle, whose recent book Experiment Eleven probes this gripping, scandalous story and its diverse global repercussions— for scientific inquiry and mentoring, for research ethics, and for the evolution of Big Pharma.
Co-presented with the History of the Health Sciences Lecture Series, Claude Moore Health Sciences Library
January 23, 2019
Joe Richman
Since 1996, the Radio Diaries project has been giving people audio recorders and working with them to report on their own lives and histories. Collaborating with teens and octogenarians, persons with chronic and terminal illness, prisoners and prison guards, gospel preachers and bra saleswomen, the famous and the unknown, the project tells extraordinary stories of ordinary life. With stories aired on NPR, BBC, This American Life, and its own podcast, Radio Diaries has pioneered a new form of citizen journalism and, along the way, garnered every major award in broadcast journalism. This Medical Center Hour welcomes Radio Diaries’ founding director, Joe Richman, to share stories and draw parallels with health care practice, where, daily, clinicians traffic in the “extraordinary stories of ordinary life.”
The Edward W. Hook Lecture in Medicine and the Arts / Medical Grand Rounds
Co-presented with the Department of Medicine, UVA
When the First Nations of Big River and Ahtahkakoop in Canada's Saskatchewan province realized they had an HIV epidemic within their rural communities, their leadership and health centers rallied community members to determine the social and structural issues behind the epidemic. One of the driving factors proved to be injection drug use. Big River and Ahtahkakoop then developed culturally competent, community-based care to address the intertwined issues of HIV, hepatitis C, and substance use. In this presentation, spokespersons from these two communities describe how they took on these epidemics and discuss the solutions that have worked for them. What can other communities struggling similarly with substance abuse and related infectious disease outbreaks learn from these First Nations' grassroots responses? Are there lessons here for communities in Virginia, where, on average, three people die each day from opioid overdose?
Co-presented with the Department of Medicine and the Center for Global Health, in conjunction with the conference, "Best Practices in Community Mobilization in Response to Substance Use and Related Epidemics"
Emily Levine does for science what Jon Stewart does for news: she critiques it, she makes it relevant, she makes it funny. She brings her experiences as a patient in search of a diagnosis and a curative path to physical health and notes that in order to regain metaphysical health, she had to enter a universe of randomness, uncertainty, and turbulence. She reasons that only quantum physics and chaos theory can make sense of this new universe, and possibly of medicine today.
A John F. Anderson Memorial Lecture
On 13 June 2013, the U.S. Supreme Court struck down patents on the hereditary breast and ovarian cancer (BRCA) genes. One company, Utah-based Myriad Genetics, claimed ownership of those genes and both marketed and processed the test for them. Myriad now controls the genetic data of all the persons tested for BRCA.
In the wake of the 9-0 ruling against Myriad, there's considerable debate about who owns this genetic information and who should control it. Should it be held by a private company or in a commons? Should control rest with the BRCA+ community? "Free the Data," a new grass-roots campaign, brings voices of BRCA+ individuals and biomedical investigators alike into this debate. In this Medical Center Hour, documentary filmmaker Joanna Rudnick, together with law and medical experts from UVA, discuss what's at stake in freeing the data.
Co-presented with the Institute for Practical Ethics and Public Life, the Department of Public Health Sciences, and the Cancer Center's Breast Care Program, UVA
The Hollingsworth Lecture in Practical Ethics
Alice Dreger’s newest book, Galileo’s Middle Finger: Heretics, Activists, and the Search for Justice in Science, had its origins in social and scientific controversies having to do with the politics of sex, especially social and medical treatment of so-called intersex individuals. Ms. Dreger’s investigations into this aspect of human identity and intersex rights engaged her with both sides of a heated debate and also with issues of freedom and justice in science. As she says, “Science and social justice require each other to be healthy, and both are critically important to human freedom. . . . [P]ursuit of evidence is probably the most pressing moral imperative of our time. All of our work as scholars, activities, and citizens of democracy depends on it. Yet it seems that, especially when questions of human identity are concerned, we’ve built up a system in which scientists and social justice advocates are fighting in ways that poison the soil on which both depend. It’s high time we think about this mess we’ve created, about what we’re doing to each other and to democracy itself.”
In this Medical Center Hour, Ms. Dreger addresses these concerns—for science, justice, and academic freedom—at a time when pursuit of knowledge can clash with established interests, worldviews, and ideas about social progress.
Co-presented with the History of the Health Sciences Lecture Series
Columbine. Virginia Tech. Ft. Hood. Huntsville. Tucson. Aurora. Newtown. The Navy Yard. Charleston. Roseburg. Gun violence, including a relentless raft of mass shootings, is epidemic today in the U.S., threatening individual safety and public health and wellbeing. The grim tally for 2015, says the Washington Post, is 294 mass shootings in 274 days. Many shooters are said to have undiagnosed or undertreated mental illness in their background.
How does psychopathology contribute to violent behavior, particularly involving firearms, over a person's life course and in the social environment? How accurate and useful are clinicians’ predictions of violence in their patients? What is an appropriate role for clinicians as “gun gatekeepers” and for mental health services generally, as part of a public-health solution to gun violence? This Medical Center Hour reviews research related to these urgent questions and explores implications for clinicians and other mental-health stakeholders.
Co-presented with the Institute for Law, Psychiatry, and Public Policy and the School of Law, UVA
A John F. Anderson Memorial Lecture
